ABSTRACT
AIM@#To study the chemical constituents from the fermentation of the endophytic fungus HP-1 of Chinese eaglewood.@*METHODS@#The chemical constituents were isolated by column chromatography on silica gel and Sephadex LH-20, and their structures were elucidated on the basis of spectroscopic analysis.@*RESULTS@#Four compounds were isolated and identified as 3α, 3β, 10β-trimethyl-decahydroazuleno[6, 7]furan-8, 9, 14-triol (1), 4-hydroxyphenylacetic acid (2), 4-hydroxyphenethyl alcohol (3), and 5-hydroxymethyl-2-furancarboxaldehyde (4).@*CONCLUSION@#Compound 1 was a new compound. Compound 2 showed antibacterial activity against Staphylococcus aureus.
Subject(s)
Anti-Bacterial Agents , Chemistry , Pharmacology , Endophytes , Chemistry , Fungi , Chemistry , Phenylacetates , Chemistry , Pharmacology , Sesquiterpenes , Chemistry , Thymelaeaceae , Microbiology , Wood , MicrobiologyABSTRACT
AIM@#To investigate the chemical constituents in the stems of Trigonostemon heterophyllus.@*METHOD@#The chemical constituents were isolated by column chromatography on silica gel, Rp-18, and Sephadex LH-20, and their structures were elucidated on the basis of spectroscopic analysis.@*RESULTS@#Three compounds were isolated and identified as a new diterpene, trigonoheterene B (1), together with two known compounds, trigonostemone (2) and trigonochinene B (3).@*CONCLUSION@#Compound 1 is new. Compounds 2 and 3 showed antibacterial activities.
Subject(s)
Diterpenes , Chemistry , Drugs, Chinese Herbal , Chemistry , Euphorbiaceae , Chemistry , Molecular Structure , Plant Stems , ChemistryABSTRACT
<p><b>OBJECTIVE</b>To study the constituents from the stems of Aquilaria sinensis.</p><p><b>METHOD</b>The chemical constituents were isolated by various column chromatographic methods. The structures were identified by spectral analysis including NMR and MS data.</p><p><b>RESULT</b>Sixteen compounds were isolated and identified as threo-buddlenol C (1), thero-ficusesquilignan A (2), erythro-buddlenol C (3), (+/-) buddlenol D (4), (-) medioresinol (5), (-) pinoresinol (6), 5'-methoxy lariciresinol (7), erythro-guaiacylglycerol-beta-coniferyl ether (8), thero-guaiacylglycerol-beta-coniferyl ether (9), herpetin (10), (+) syringaresinol (11), curuilignan (12), ciwujiatone (13), coniferyl alcohol (14), 3, 4, 5-trimethoxyphenol (15) and cucurbitacin (16).</p><p><b>CONCLUSION</b>All the compounds, except for 11-13 were obtained from A. sinensis for the first time.</p>
Subject(s)
Drugs, Chinese Herbal , Chemistry , Furans , Chemistry , Lignans , Chemistry , Magnetic Resonance Spectroscopy , Molecular Structure , Plant Stems , Chemistry , Spectrometry, Mass, Electrospray Ionization , Thymelaeaceae , ChemistryABSTRACT
To investigate the chemical constituents of the endophytic fungus Penicillium sp. FJ-1 of Ceriops tagal, the chemical constituents were isolated by column chromatography on silica gel and Sephadex LH-20. Their structures were elucidated on the basis of spectroscopic analysis. Their antibacterial activity was tested by paper disco diffusion method. Two compounds were isolated and identified as 7-hydroxy-deoxytalaroflavone (1), and deoxytalaroflavone (2). Compound 1 is a new compound, and compounds 1 and 2 showed weak activity against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus.
Subject(s)
Anti-Bacterial Agents , Chemistry , Pharmacology , Flavones , Chemistry , Pharmacology , Methicillin-Resistant Staphylococcus aureus , Molecular Structure , Penicillium , Chemistry , Rhizophoraceae , Microbiology , Staphylococcus aureusABSTRACT
Objective: To investigate the chemical constituents in the leaves of Ilex kudingcha. Methods: Repeated column chromatography with silical gel, maroporous resin column, Sephadex LH-20, and preparative HPLC were used to isolate the chemical constituents, and their structures were elucidated on the basis of spectral data. Results: Eight compounds were isolated and identified as mateglycoside D (1), methyl caffeate (2), vanillin (3), gallic acid (4), caffeic acid (5), β-sitosterol (6), p-hydroxy-benzaldehyde (7), and ferulic acid (8). Conclusion: Compounds 2 and 7 are first obtained from the plants of Ilex L., and compounds 1,3,4, and 8 are first obtained from I. kudingcha.